PAK1 autoinhibition is relieved by Cdc42 binding and autophosphorylation

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This model was created by using structural information provided by The Protein Data Bank
H.M. Berman, J. Westbrook, Z. Feng, G. Gilliland, T.N. Bhat, H. Weissig, I.N. Shindyalov, P.E. Bourne:The Protein Data Bank. Nucleic Acids Research, 28pp. 235-242 (2000)

Lei, M., Lu, W., Meng, W., Parrini, M-C., Eck, M. J., Mayer, B. J., Harrison, S. C.: Structure of Pak1 in an Autoinhibited Conformation Reveals a Multistage Activation Switch Cell (Cambridge,Mass.) 102 pp. 387 (2000)

Morreale, A., Venkatesan, M., Mott, H. R., Owen, D., Nietlispach, D., Lowe, P. N., Laue, E. D.: Solution Structure of Cdc42 Bound to the Gtpase Binding Domian of Pak Nat.Struct.Biol. 7 pp. 384 (2000)
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